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Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences

BACKGROUND: Deep immune receptor sequencing, RepSeq, provides unprecedented opportunities for identifying and studying condition-associated T-cell clonotypes, represented by T-cell receptor (TCR) CDR3 sequences. However, due to the immense diversity of the immune repertoire, identification of condit...

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Detalles Bibliográficos
Autores principales:	Yohannes, Dawit A., Kaukinen, Katri, Kurppa, Kalle, Saavalainen, Päivi, Greco, Dario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993519/ https://www.ncbi.nlm.nih.gov/pubmed/33765908 http://dx.doi.org/10.1186/s12859-021-04087-7

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