Corticotroph Aggressive Pituitary Tumors and Carcinomas Frequently Harbor ATRX Mutations

CONTEXT: Aggressive pituitary tumors (APTs) are characterized by unusually rapid growth and lack of response to standard treatment. About 1% to 2% develop metastases being classified as pituitary carcinomas (PCs). For unknown reasons, the corticotroph tumors are overrepresented among APTs and PCs. M...

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Detalles Bibliográficos
Autores principales: Casar-Borota, Olivera, Boldt, Henning Bünsow, Engström, Britt Edén, Andersen, Marianne Skovsager, Baussart, Bertrand, Bengtsson, Daniel, Berinder, Katarina, Ekman, Bertil, Feldt-Rasmussen, Ulla, Höybye, Charlotte, Jørgensen, Jens Otto L, Kolnes, Anders Jensen, Korbonits, Márta, Rasmussen, Åse Krogh, Lindsay, John R, Loughrey, Paul Benjamin, Maiter, Dominique, Manojlovic-Gacic, Emilija, Pahnke, Jens, Poliani, Pietro Luigi, Popovic, Vera, Ragnarsson, Oskar, Schalin-Jäntti, Camilla, Scheie, David, Tóth, Miklós, Villa, Chiara, Wirenfeldt, Martin, Kunicki, Jacek, Burman, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Clinical Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993578/
https://www.ncbi.nlm.nih.gov/pubmed/33106857
http://dx.doi.org/10.1210/clinem/dgaa749

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