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Identification of protein quality control regulators using a Drosophila model of TPI deficiency

Triosephosphate isomerase (TPI) deficiency (Df) is a rare recessive metabolic disorder that manifests as hemolytic anemia, locomotor impairment, and progressive neurodegeneration. Research suggests that TPI Df mutations, including the “common” TPI(E105D) mutation, result in reduced TPI protein stabi...

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Detalles Bibliográficos
Autores principales:	Hrizo, Stacy L., Eicher, Samantha L., Myers, Tracey D., McGrath, Ian, Wodrich, Andrew P. K., Venkatesh, Hemanth, Manjooran, Daniel, Swoger, Sabrina, Gagnon, Kim, Bruskin, Matthew, Lebedev, Maria V., Zheng, Sherry, Vitantonio, Ana, Kim, Sungyoun, Lamb, Zachary J., Vogt, Andreas, Ruzhnikov, Maura R.Z., Palladino, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993632/ https://www.ncbi.nlm.nih.gov/pubmed/33600953 http://dx.doi.org/10.1016/j.nbd.2021.105299

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