Cargando…

Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing

Tumors are complex ecosystems harboring multiple cell types which might play a critical role in tumor progression and treatment response. The endometrial epithelial cell identities and immune microenvironment of endometrial carcinoma (ECC) are poorly characterized. In this study, a cellular map of e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Yu-e, Li, Yiran, Cai, Bailian, He, Qizhi, Chen, Guofang, Wang, Mengfei, Wang, Kai, Wan, Xiaoping, Yan, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993685/ https://www.ncbi.nlm.nih.gov/pubmed/33429363 http://dx.doi.org/10.18632/aging.202288

Ejemplares similares

Hypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA
por: Chen, Guofang, et al.
Publicado: (2020)

POLE Mutation Characteristics in a Chinese Cohort with Endometrial Carcinoma
por: Li, Yiran, et al.
Publicado: (2020)

Endometrial Tumors with MSI-H and dMMR Share a Similar Tumor Immune Microenvironment
por: Song, Yunfeng, et al.
Publicado: (2021)

Integrated Analysis of Microbiome and Transcriptome Data Reveals the Interplay Between Commensal Bacteria and Fibrin Degradation in Endometrial Cancer
por: Li, Chao, et al.
Publicado: (2021)

Collagen triple helix repeat containing 1 promotes endometrial cancer cell migration by activating the focal adhesion kinase signaling pathway
por: Hu, Xiang, et al.
Publicado: (2020)

NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis
por: Han, Tong, et al.
Publicado: (2020)

Single-Cell RNA-Sequencing Reveals Interactions between Endometrial Stromal Cells, Epithelial Cells, and Lymphocytes during Mouse Embryo Implantation
por: Jiang, Luhan, et al.
Publicado: (2022)

Single‐cell sequencing reveals the heterogeneity and intratumoral crosstalk in human endometrial cancer
por: Yu, Zhicheng, et al.
Publicado: (2022)

p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer
por: Wen, Xiaoli, et al.
Publicado: (2020)

Adenomyosis-derived extracellular vesicles endow endometrial epithelial cells with an invasive phenotype through epithelial-mesenchymal transition
por: Chen, Dayong, et al.
Publicado: (2020)

Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility
por: Saatcioglu, Hatice Duygu, et al.
Publicado: (2019)

Chemokines as the modulators of endometrial epithelial cells remodelling
por: Złotkowska, A, et al.
Publicado: (2019)

The Elusive Endometrial Epithelial Stem/Progenitor Cells
por: Cousins, Fiona L., et al.
Publicado: (2021)

The proliferative effect of cortisol on bovine endometrial epithelial cells
por: Dong, Junsheng, et al.
Publicado: (2019)

Functional expression of the mechanosensitive PIEZO1 channel in primary endometrial epithelial cells and endometrial organoids
por: Hennes, Aurélie, et al.
Publicado: (2019)

TRIB3 suppresses proliferation and invasion and promotes apoptosis of endometrial cancer cells by regulating the AKT signaling pathway
por: Qu, Junjie, et al.
Publicado: (2019)

HHV-6A Infection of Endometrial Epithelial Cells Induces Increased Endometrial NK Cell-Mediated Cytotoxicity
por: Caselli, Elisabetta, et al.
Publicado: (2017)

Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis
por: Shih, Andrew J., et al.
Publicado: (2022)

A Clinical Comparative Study of Two Different Endometrial Cell Samplers for Evaluation of Endometrial Lesions by Cytopathological Diagnosis
por: Lv, Shulan, et al.
Publicado: (2020)

Stem cell protein Piwil1 endowed endometrial cancer cells with stem-like properties via inducing epithelial-mesenchymal transition
por: Chen, Zheng, et al.
Publicado: (2015)

Establishment and characterization of immortalized bovine endometrial epithelial cells
por: Bai, Hanako, et al.
Publicado: (2014)

Campylobacter fetus is Internalized by Bovine Endometrial Epithelial Cells
por: CAMPOS-MÚZQUIZ, LIZETH GUADALUPE, et al.
Publicado: (2019)

SOX17 is a tumor suppressor in endometrial cancer
por: Zhang, Yongli, et al.
Publicado: (2016)

Progesterone Signaling in Endometrial Epithelial Organoids
por: Hewitt, Sylvia C., et al.
Publicado: (2022)

Endometrial hyperplasia with loss of APC in a novel population of Lyz2-expressing mouse endometrial epithelial cells
por: Kitchen-Goosen, Susan M, et al.
Publicado: (2022)

Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma
por: Chang, Shing-Jyh, et al.
Publicado: (2009)

Upregulation of TrkB Promotes Epithelial-Mesenchymal Transition and Anoikis Resistance in Endometrial Carcinoma
por: Bao, Wei, et al.
Publicado: (2013)

MicroRNA heterogeneity in endometrial cancer cell lines revealed by deep sequencing
por: LU, JIAFENG, et al.
Publicado: (2015)

AMF/PGI-mediated tumorigenesis through MAPK-ERK signaling in endometrial carcinoma
por: Li, Yiran, et al.
Publicado: (2015)

Single-cell transcriptome analysis of endometrial tissue
por: Krjutškov, K., et al.
Publicado: (2016)

SOX17 increases the cisplatin sensitivity of an endometrial cancer cell line
por: Zhang, Yongli, et al.
Publicado: (2016)

Bisphenol S Increases Cell Number and Stimulates Migration of Endometrial Epithelial Cells
por: Benjamin, Kimberly, et al.
Publicado: (2022)

Isolation of Mouse Endometrial Epithelial and Stromal Cells for In Vitro Decidualization
por: De Clercq, Katrien, et al.
Publicado: (2017)

Author Correction: Chemokines as the modulators of endometrial epithelial cells remodelling
por: Złotkowska, A., et al.
Publicado: (2019)

LPS-treatment of bovine endometrial epithelial cells causes differential DNA methylation of genes associated with inflammation and endometrial function
por: Jhamat, Naveed, et al.
Publicado: (2020)

Autocrine motility factor promotes endometrial cancer progression by targeting GPER-1
por: Li, Yiran, et al.
Publicado: (2019)

MicroRNA-93 Promotes Epithelial–Mesenchymal Transition of Endometrial Carcinoma Cells
por: Chen, Shuo, et al.
Publicado: (2016)

PTEN Sequence Analysis in Endometrial Hyperplasia and Endometrial Carcinoma in Slovak Women
por: Gbelcová, H., et al.
Publicado: (2015)

Correction: AMF/PGI-mediated tumorigenesis through MAPK-ERK signaling in endometrial carcinoma
por: Li, Yiran, et al.
Publicado: (2020)

Endometrial Stem/Progenitor Cells–Their Role in Endometrial Repair and Regeneration
por: Cousins, Fiona L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_69id760n53v0dj2i4uek4cgm0m