β cell aging and age-related diabetes

Type 2 diabetes is characterized by insulin resistance and loss of β cell mass and function. Aging is considered as a major risk factor for development of type 2 diabetes. However, the roles of pancreatic β cell senescence and systemic aging in the pathogenesis of type 2 diabetes in elderly people r...

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Detalles Bibliográficos
Autores principales: Zhu, Min, Liu, Xiaohong, Liu, Wen, Lu, Yanrong, Cheng, Jingqiu, Chen, Younan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993693/
https://www.ncbi.nlm.nih.gov/pubmed/33686020
http://dx.doi.org/10.18632/aging.202593
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author Zhu, Min
Liu, Xiaohong
Liu, Wen
Lu, Yanrong
Cheng, Jingqiu
Chen, Younan
author_facet Zhu, Min
Liu, Xiaohong
Liu, Wen
Lu, Yanrong
Cheng, Jingqiu
Chen, Younan
author_sort Zhu, Min
collection PubMed
description Type 2 diabetes is characterized by insulin resistance and loss of β cell mass and function. Aging is considered as a major risk factor for development of type 2 diabetes. However, the roles of pancreatic β cell senescence and systemic aging in the pathogenesis of type 2 diabetes in elderly people remain poorly understood. In this review, we aimed to discuss the current findings and viewpoints focusing on β cell aging and the development of type 2 diabetes.
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spelling pubmed-79936932021-04-06 β cell aging and age-related diabetes Zhu, Min Liu, Xiaohong Liu, Wen Lu, Yanrong Cheng, Jingqiu Chen, Younan Aging (Albany NY) Review Type 2 diabetes is characterized by insulin resistance and loss of β cell mass and function. Aging is considered as a major risk factor for development of type 2 diabetes. However, the roles of pancreatic β cell senescence and systemic aging in the pathogenesis of type 2 diabetes in elderly people remain poorly understood. In this review, we aimed to discuss the current findings and viewpoints focusing on β cell aging and the development of type 2 diabetes. Impact Journals 2021-03-03 /pmc/articles/PMC7993693/ /pubmed/33686020 http://dx.doi.org/10.18632/aging.202593 Text en Copyright: © 2021 Zhu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review
Zhu, Min
Liu, Xiaohong
Liu, Wen
Lu, Yanrong
Cheng, Jingqiu
Chen, Younan
β cell aging and age-related diabetes
title β cell aging and age-related diabetes
title_full β cell aging and age-related diabetes
title_fullStr β cell aging and age-related diabetes
title_full_unstemmed β cell aging and age-related diabetes
title_short β cell aging and age-related diabetes
title_sort β cell aging and age-related diabetes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993693/
https://www.ncbi.nlm.nih.gov/pubmed/33686020
http://dx.doi.org/10.18632/aging.202593
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AT chenyounan bcellagingandagerelateddiabetes

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