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Transcription factor ELK1 accelerates aerobic glycolysis to enhance osteosarcoma chemoresistance through miR-134/PTBP1 signaling cascade

Osteosarcoma is a malignancy that primarily affects children and young adults. The poor survival is largely attributed to acquisition of chemoresistance. Thus, the current study aimed to elucidate the role of ELK1/miR-134/PTBP1 signaling cascade in osteosarcoma chemoresistance. Doxorubicin (DXR)-res...

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Detalles Bibliográficos
Autores principales:	Zhang, Qiang, Wu, Jiaqi, Zhang, Xiangfeng, Cao, Le, Wu, Yongping, Miao, Xudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993718/ https://www.ncbi.nlm.nih.gov/pubmed/33621196 http://dx.doi.org/10.18632/aging.202538

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