Cargando…
Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines
Expression of the protease sensing receptor, protease activated receptor-2 (PAR2), is elevated in a variety of cancers and has been promoted as a potential therapeutic target. With the development of potent antagonists for this receptor, we hypothesised that they could be used to treat renal cell ca...
Autores principales: | Morais, Christudas, Rajandram, Retnagowri, Blakeney, Jade S., Iyer, Abishek, Suen, Jacky Y., Johnson, David W., Gobe, Glenda C., Fairlie, David P., Vesey, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993771/ https://www.ncbi.nlm.nih.gov/pubmed/33765016 http://dx.doi.org/10.1371/journal.pone.0248983 |
Ejemplares similares
-
Functional significance of erythropoietin in renal cell carcinoma
por: Morais, Christudas, et al.
Publicado: (2013) -
Characterisation of the Morphological, Functional and Molecular Changes in Sunitinib-Resistant Renal Cell Carcinoma Cells
por: Kamli, Hossam, et al.
Publicado: (2018) -
Evaluation of steroid hormones and their receptors in development and progression of renal cell carcinoma
por: Bennett, Nigel C, et al.
Publicado: (2014) -
Decreased Expression of Inhibitor of Caspase-Activated DNase (ICAD) in Renal Cell Carcinoma – Tissue Microarray of Human Samples
por: Rajandram, Retnagowri, et al.
Publicado: (2016) -
PAR2-Induced Tissue Factor Synthesis by Primary Cultures of Human Kidney Tubular Epithelial Cells Is Modified by Glucose Availability
por: Humphries, Tyrone L. R., et al.
Publicado: (2021)