Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

The Mycobacterium tuberculosis complex (MTBC) is a group of related pathogens that cause tuberculosis (TB) in mammals. MTBC species are distinguished by their ability to sustain in distinct host populations. While Mycobacterium bovis (Mbv) sustains transmission cycles in cattle and wild animals and...

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Detalles Bibliográficos
Autores principales: Queval, Christophe J., Fearns, Antony, Botella, Laure, Smyth, Alicia, Schnettger, Laura, Mitermite, Morgane, Wooff, Esen, Villarreal-Ramos, Bernardo, Garcia-Jimenez, Waldo, Heunis, Tiaan, Trost, Matthias, Werling, Dirk, Salguero, Francisco J., Gordon, Stephen V., Gutierrez, Maximiliano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993774/
https://www.ncbi.nlm.nih.gov/pubmed/33720986
http://dx.doi.org/10.1371/journal.ppat.1009410

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