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DRP1 haploinsufficiency attenuates cardiac ischemia/reperfusion injuries

Mitochondrial dynamics is a possible modulator of myocardial ischemia/reperfusion injuries (IRI). We previously reported that mice partially deficient in the fusion protein OPA1 exhibited higher IRI. Therefore, we investigated whether deficiency in the fission protein DRP1 encoded by Dnm1l gene woul...

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Detalles Bibliográficos
Autores principales: Bouche, Laura, Kamel, Rima, Tamareille, Sophie, Garcia, Gabriel, Villedieu, Camille, Pillot, Bruno, Gueguen, Naïg, Chehaitly, Ahmad, Chao de la Barca, Juan Manuel, Beaumont, Justine, Baetz, Delphine, Ovize, Michel, Sesaki, Hiromi, Henrion, Daniel, Reynier, Pascal, Lenaers, Guy, Prunier, Fabrice, Mirebeau-Prunier, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993837/
https://www.ncbi.nlm.nih.gov/pubmed/33765018
http://dx.doi.org/10.1371/journal.pone.0248554