Clinical Relevance of Pre-Existing and Treatment-Induced Anti-Poly(Ethylene Glycol) Antibodies

ABSTRACT: Poly(ethylene glycol) (PEG) is a nontoxic, hydrophilic polymer that is often covalently attached to proteins, drugs, tissues, or materials; a procedure commonly referred to as PEGylation. PEGylation improves solubility, circulation time, and reduces immunogenicity of therapeutic molecules....

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Detalles Bibliográficos
Autores principales: Freire Haddad, Helena, Burke, Jacqueline A., Scott, Evan A., Ameer, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993857/
https://www.ncbi.nlm.nih.gov/pubmed/33786367
http://dx.doi.org/10.1007/s40883-021-00198-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993857/
https://www.ncbi.nlm.nih.gov/pubmed/33786367
http://dx.doi.org/10.1007/s40883-021-00198-y

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