Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis

Atherosclerosis is a disease of chronic inflammation. We investigated the roles of the cytokines IL-4 and IL-13, the classical activators of STAT6, in the resolution of atherosclerosis inflammation. Using Il4(-/-)Il13(-/-) mice, resolution was impaired, and in control mice, in both progressing and r...

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Detalles Bibliográficos
Autores principales: Weinstock, Ada, Rahman, Karishma, Yaacov, Or, Nishi, Hitoo, Menon, Prashanthi, Nikain, Cyrus A, Garabedian, Michela L, Pena, Stephanie, Akbar, Naveed, Sansbury, Brian E, Heffron, Sean P, Liu, Jianhua, Marecki, Gregory, Fernandez, Dawn, Brown, Emily J, Ruggles, Kelly V, Ramsey, Stephen A, Giannarelli, Chiara, Spite, Matthew, Choudhury, Robin P, Loke, P'ng, Fisher, Edward A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994001/
https://www.ncbi.nlm.nih.gov/pubmed/33720008
http://dx.doi.org/10.7554/eLife.67932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994001/
https://www.ncbi.nlm.nih.gov/pubmed/33720008
http://dx.doi.org/10.7554/eLife.67932

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