BAY 60-6583 Enhances the Antitumor Function of Chimeric Antigen Receptor-Modified T Cells Independent of the Adenosine A2b Receptor

Chimeric antigen receptor (CAR) T cells are powerful in eradicating hematological malignancies, but their efficacy is limited in treating solid tumors. One of the barriers is the immunosuppressive response induced by immunomodulatory signaling pathways. Pharmacological targeting of these immunosuppr...

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Detalles Bibliográficos
Autores principales: Tang, Jiaxing, Zou, Yan, Li, Long, Lu, Fengping, Xu, Hongtao, Ren, Pengxuan, Bai, Fang, Niedermann, Gabriele, Zhu, Xuekai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994267/
https://www.ncbi.nlm.nih.gov/pubmed/33776765
http://dx.doi.org/10.3389/fphar.2021.619800

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