Cancer-associated cells release citrate to support tumour metastatic progression

Citrate is important for lipid synthesis and epigenetic regulation in addition to ATP production. We have previously reported that cancer cells import extracellular citrate via the pmCiC transporter to support their metabolism. Here, we show for the first time that citrate is supplied to cancer by c...

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Detalles Bibliográficos
Autores principales: Drexler, Konstantin, Schmidt, Katharina M, Jordan, Katrin, Federlin, Marianne, Milenkovic, Vladimir M, Liebisch, Gerhard, Artati, Anna, Schmidl, Christian, Madej, Gregor, Tokarz, Janina, Cecil, Alexander, Jagla, Wolfgang, Haerteis, Silke, Aung, Thiha, Wagner, Christine, Kolodziejczyk, Maria, Heinke, Stefanie, Stanton, Evan H, Schwertner, Barbara, Riegel, Dania, Wetzel, Christian H, Buchalla, Wolfgang, Proescholdt, Martin, Klein, Christoph A, Berneburg, Mark, Schlitt, Hans J, Brabletz, Thomas, Ziegler, Christine, Parkinson, Eric K, Gaumann, Andreas, Geissler, Edward K, Adamski, Jerzy, Haferkamp, Sebastian, Mycielska, Maria E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994318/
https://www.ncbi.nlm.nih.gov/pubmed/33758075
http://dx.doi.org/10.26508/lsa.202000903

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