Cargando…
Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study
Although cranial autonomic symptoms (CAS) are typical in cluster headache (CH), some individuals with CH show no CAS during their headache attacks. Probable cluster headache (PCH) is a subtype of CH that fulfils all but one criterion of CH. This study aimed to investigate the frequency and clinical...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994319/ https://www.ncbi.nlm.nih.gov/pubmed/33767287 http://dx.doi.org/10.1038/s41598-021-86408-7 |
_version_ | 1783669730377203712 |
---|---|
author | Chu, Min Kyung Kim, Byung-Su Chung, Pil-Wook Kim, Byung-Kun Lee, Mi Ji Park, Jeong Wook Ahn, Jin-Young Bae, Dae Woong Song, Tae-Jin Sohn, Jong-Hee Oh, Kyungmi Kim, Daeyoung Kim, Jae-Moon Kim, Soo-Kyoung Choi, Yun-Ju Chung, Jae Myun Moon, Heui-Soo Chung, Chin-Sang Park, Kwang-Yeol Cho, Soo-Jin |
author_facet | Chu, Min Kyung Kim, Byung-Su Chung, Pil-Wook Kim, Byung-Kun Lee, Mi Ji Park, Jeong Wook Ahn, Jin-Young Bae, Dae Woong Song, Tae-Jin Sohn, Jong-Hee Oh, Kyungmi Kim, Daeyoung Kim, Jae-Moon Kim, Soo-Kyoung Choi, Yun-Ju Chung, Jae Myun Moon, Heui-Soo Chung, Chin-Sang Park, Kwang-Yeol Cho, Soo-Jin |
author_sort | Chu, Min Kyung |
collection | PubMed |
description | Although cranial autonomic symptoms (CAS) are typical in cluster headache (CH), some individuals with CH show no CAS during their headache attacks. Probable cluster headache (PCH) is a subtype of CH that fulfils all but one criterion of CH. This study aimed to investigate the frequency and clinical features of CH and PCH without CAS in comparison to those with CAS. We analysed data from the Korea Cluster Headache Registry, a prospective multicentre registry involving data from 16 hospitals. Of the 216 participants with CH and 26 with PCH, 19 (8.8%) and 7 (26.9%), respectively, did not have CAS. Participants with CH without CAS exhibited less severe anxiety (General Anxiety Disorder-7 score, median [interquartile range], 2.0 [1.0–6.0] vs 8.0 [3.0–12.0], p = 0.001) and depression (Patient Health Questionnaire-9 score, 3.0 [1.0–7.0] vs 7.0 [3.0–11.0], p = 0.042) than those with CAS. Among participants with PCH, headache intensity was less severe in participants without CAS than in those with CAS (numeric rating scale, 8.0 [7.0–8.0] vs 9.5 [8.0–10.0], p = 0.015). In conclusion, a significant proportion of participants with CH and PCH did not have CAS. Some clinical features of CH and PCH differed based on the presence of CAS. |
format | Online Article Text |
id | pubmed-7994319 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-79943192021-03-29 Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study Chu, Min Kyung Kim, Byung-Su Chung, Pil-Wook Kim, Byung-Kun Lee, Mi Ji Park, Jeong Wook Ahn, Jin-Young Bae, Dae Woong Song, Tae-Jin Sohn, Jong-Hee Oh, Kyungmi Kim, Daeyoung Kim, Jae-Moon Kim, Soo-Kyoung Choi, Yun-Ju Chung, Jae Myun Moon, Heui-Soo Chung, Chin-Sang Park, Kwang-Yeol Cho, Soo-Jin Sci Rep Article Although cranial autonomic symptoms (CAS) are typical in cluster headache (CH), some individuals with CH show no CAS during their headache attacks. Probable cluster headache (PCH) is a subtype of CH that fulfils all but one criterion of CH. This study aimed to investigate the frequency and clinical features of CH and PCH without CAS in comparison to those with CAS. We analysed data from the Korea Cluster Headache Registry, a prospective multicentre registry involving data from 16 hospitals. Of the 216 participants with CH and 26 with PCH, 19 (8.8%) and 7 (26.9%), respectively, did not have CAS. Participants with CH without CAS exhibited less severe anxiety (General Anxiety Disorder-7 score, median [interquartile range], 2.0 [1.0–6.0] vs 8.0 [3.0–12.0], p = 0.001) and depression (Patient Health Questionnaire-9 score, 3.0 [1.0–7.0] vs 7.0 [3.0–11.0], p = 0.042) than those with CAS. Among participants with PCH, headache intensity was less severe in participants without CAS than in those with CAS (numeric rating scale, 8.0 [7.0–8.0] vs 9.5 [8.0–10.0], p = 0.015). In conclusion, a significant proportion of participants with CH and PCH did not have CAS. Some clinical features of CH and PCH differed based on the presence of CAS. Nature Publishing Group UK 2021-03-25 /pmc/articles/PMC7994319/ /pubmed/33767287 http://dx.doi.org/10.1038/s41598-021-86408-7 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Chu, Min Kyung Kim, Byung-Su Chung, Pil-Wook Kim, Byung-Kun Lee, Mi Ji Park, Jeong Wook Ahn, Jin-Young Bae, Dae Woong Song, Tae-Jin Sohn, Jong-Hee Oh, Kyungmi Kim, Daeyoung Kim, Jae-Moon Kim, Soo-Kyoung Choi, Yun-Ju Chung, Jae Myun Moon, Heui-Soo Chung, Chin-Sang Park, Kwang-Yeol Cho, Soo-Jin Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
title | Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
title_full | Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
title_fullStr | Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
title_full_unstemmed | Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
title_short | Clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
title_sort | clinical features of cluster headache without cranial autonomic symptoms: results from a prospective multicentre study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994319/ https://www.ncbi.nlm.nih.gov/pubmed/33767287 http://dx.doi.org/10.1038/s41598-021-86408-7 |
work_keys_str_mv | AT chuminkyung clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT kimbyungsu clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT chungpilwook clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT kimbyungkun clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT leemiji clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT parkjeongwook clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT ahnjinyoung clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT baedaewoong clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT songtaejin clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT sohnjonghee clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT ohkyungmi clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT kimdaeyoung clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT kimjaemoon clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT kimsookyoung clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT choiyunju clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT chungjaemyun clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT moonheuisoo clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT chungchinsang clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT parkkwangyeol clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy AT chosoojin clinicalfeaturesofclusterheadachewithoutcranialautonomicsymptomsresultsfromaprospectivemulticentrestudy |