BIMG-10. IDH1 MUTATIONS INDUCE ORGANELLE DEFECTS VIA DYSREGULATED PHOSPHOLIPIDS

BACKGROUND: Metabolic alterations of lipids have been identified as a hallmark of neoplasms, with the most prevalent being the balance between saturated fatty acid (SFA) and monosaturated fatty acid (MUFA). Stearoyl-CoA desaturase1 (SCD1), converting SFA to MUFA, is increased in many cancers, leadin...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tomohiro, Lita, Adrian, Zhang, Lumin, Rodado, Victor Ruiz, Dowdy, Tyrone, Gilbert, Mark, Larion, Mioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994379/
http://dx.doi.org/10.1093/noajnl/vdab024.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994379/
http://dx.doi.org/10.1093/noajnl/vdab024.009

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