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Model-based deep embedding for constrained clustering analysis of single cell RNA-seq data

Clustering is a critical step in single cell-based studies. Most existing methods support unsupervised clustering without the a priori exploitation of any domain knowledge. When confronted by the high dimensionality and pervasive dropout events of scRNA-Seq data, purely unsupervised clustering metho...

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Detalles Bibliográficos
Autores principales:	Tian, Tian, Zhang, Jie, Lin, Xiang, Wei, Zhi, Hakonarson, Hakon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994574/ https://www.ncbi.nlm.nih.gov/pubmed/33767149 http://dx.doi.org/10.1038/s41467-021-22008-3

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