SPINK7 expression changes accompanied by HER2, P53 and RB1 can be relevant in predicting oral squamous cell carcinoma at a molecular level

The oral squamous cell carcinoma (OSCC), which has a high morbidity rate, affects patients worldwide. Changes in SPINK7 in precancerous lesions could promote oncogenesis. Our aim was to evaluate SPINK7 as a potential molecular biomarker which predicts OSCC stages, compared to: HER2, TP53, RB1, NFKB...

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Detalles Bibliográficos
Autores principales: Pennacchiotti, Gina, Valdés-Gutiérrez, Fabio, González-Arriagada, Wilfredo Alejandro, Montes, Héctor Federico, Parra, Judith Maria Roxana, Guida, Valeria Andrea, Gómez, Silvina Esther, Guerrero-Gimenez, Martin Eduardo, Fernandez-Muñoz, Juan Manuel, Zoppino, Felipe Carlos Martin, Carón, Rubén Walter, Ezquer, Marcelo Eduardo, Fernández-Ramires, Ricardo, Bruna, Flavia Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994578/
https://www.ncbi.nlm.nih.gov/pubmed/33767253
http://dx.doi.org/10.1038/s41598-021-86208-z

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