Treatment With Calcineurin Inhibitor FK506 Attenuates Noise-Induced Hearing Loss

Attenuation of noise-induced hair cell loss and noise-induced hearing loss (NIHL) by treatment with FK506 (tacrolimus), a calcineurin (CaN/PP2B) inhibitor used clinically as an immunosuppressant, has been previously reported, but the downstream mechanisms of FK506-attenuated NIHL remain unknown. Her...

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Detalles Bibliográficos
Autores principales: He, Zu-Hong, Pan, Song, Zheng, Hong-Wei, Fang, Qiao-Jun, Hill, Kayla, Sha, Su-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994600/
https://www.ncbi.nlm.nih.gov/pubmed/33777956
http://dx.doi.org/10.3389/fcell.2021.648461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994600/
https://www.ncbi.nlm.nih.gov/pubmed/33777956
http://dx.doi.org/10.3389/fcell.2021.648461

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