The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5

B cells have essential functions in multiple sclerosis and in its mouse model, experimental autoimmune encephalomyelitis, both as drivers and suppressors of the disease. The suppressive effects are driven by a regulatory B cell (Breg) population that functions, primarily but not exclusively, via the...

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Detalles Bibliográficos
Autores principales: Radomir, Lihi, Kramer, Matthias P., Perpinial, Michal, Schottlender, Nofar, Rabani, Stav, David, Keren, Wiener, Anna, Lewinsky, Hadas, Becker-Herman, Shirly, Aharoni, Rina, Milo, Ron, Mauri, Claudia, Shachar, Idit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994628/
https://www.ncbi.nlm.nih.gov/pubmed/33767202
http://dx.doi.org/10.1038/s41467-021-22230-z

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