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Effects of Recombinant Human Growth Hormone on the Onset of Puberty, Leydig Cell Differentiation, Spermatogenesis and Hypothalamic KISS1 Expression in Immature Male Rats

PURPOSE: Recombinant human growth hormone (rhGH) has been used to treat short stature and rhGH-related syndromes. However, there are concerns that rhGH-treatment may cause precocious puberty. We investigated the effects of rhGH-treatment on the puberty onset, sexual maturation, androgen production,...

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Detalles Bibliográficos
Autores principales: Huh, Kyoung, Nah, Won Heun, Xu, Yang, Park, Mi Jung, Gye, Myung Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994663/
https://www.ncbi.nlm.nih.gov/pubmed/33474850
http://dx.doi.org/10.5534/wjmh.200152