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Structural and molecular dynamics investigations of ligand stabilization via secondary binding site interactions in Paenibacillus xylanivorans GH11 xylanase

Glycoside hydrolases (GHs) are essential for plant biomass deconstruction. GH11 family consist of endo-β-1,4-xylanases which hydrolyze xylan, the second most abundant cell wall biopolymer after cellulose, into small bioavailable oligomers. Structural requirements for enzymatic mechanism of xylan hyd...

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Detalles Bibliográficos
Autores principales: Briganti, Lorenzo, Capetti, Caio, Pellegrini, Vanessa O.A., Ghio, Silvina, Campos, Eleonora, Nascimento, Alessandro S., Polikarpov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994722/
https://www.ncbi.nlm.nih.gov/pubmed/33815691
http://dx.doi.org/10.1016/j.csbj.2021.03.002