Cargando…
Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy
The tumorigenicity and toxicity of induced pluripotent stem cells (iPSCs) and their derivatives are major safety concerns in their clinical application. Recently, we developed granulocyte-macrophage colony-stimulating factor (GM-CSF)-producing proliferating myeloid cells (GM-pMCs) from mouse iPSCs a...
Autores principales: | Mashima, Hiroaki, Zhang, Rong, Kobayashi, Tsuyoshi, Tsukamoto, Hirotake, Liu, Tianyi, Iwama, Tatsuaki, Hagiya, Yuichiro, Yamamoto, Masateru, Fukushima, Satoshi, Okada, Seiji, Idiris, Alimjan, Kaneko, Shin, Nakatsura, Tetsuya, Ohdan, Hideki, Uemura, Yasushi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994724/ https://www.ncbi.nlm.nih.gov/pubmed/33816647 http://dx.doi.org/10.1016/j.omtm.2021.03.002 |
Ejemplares similares
-
Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response
por: Mashima, Hiroaki, et al.
Publicado: (2020) -
Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
por: Sato, Hiroki, et al.
Publicado: (2016) -
A novel cardiac differentiation method of a large number and uniformly-sized spheroids using microfabricated culture vessels
por: Miwa, Tatsuaki, et al.
Publicado: (2020) -
Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate
por: SUGAI, SHIORI, et al.
Publicado: (2016) -
Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model
por: Fujinami, Norihiro, et al.
Publicado: (2016)