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E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1

The ubiquitin-proteasome system (UPS) is a regulated mechanism of intracellular protein degradation and turnover, and its dysfunction is associated with various diseases including cancer. UBR5, an E3 ubiquitin ligase, is emerging as an important regulator of the UPS in cancers, but its role in pancr...

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Detalles Bibliográficos
Autores principales:	Li, Jin, Zhang, Wei, Gao, Jian, Du, Min, Li, Huimin, Li, Mengge, Cong, Hui, Fang, Yuan, Liang, Yiyi, Zhao, Dan, Xiang, Gang, Ma, Xiaojing, Yao, Ming, Tu, Hong, Gan, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994773/ https://www.ncbi.nlm.nih.gov/pubmed/33777788 http://dx.doi.org/10.3389/fonc.2021.634167

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