Cargando…
Natural product fragment combination to performance-diverse pseudo-natural products
Natural product structure and fragment-based compound development inspire pseudo-natural product design through different combinations of a given natural product fragment set to compound classes expected to be chemically and biologically diverse. We describe the synthetic combination of the fragment...
Autores principales: | Grigalunas, Michael, Burhop, Annina, Zinken, Sarah, Pahl, Axel, Gally, José-Manuel, Wild, Niklas, Mantel, Yannik, Sievers, Sonja, Foley, Daniel J., Scheel, Rebecca, Strohmann, Carsten, Antonchick, Andrey P., Waldmann, Herbert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994817/ https://www.ncbi.nlm.nih.gov/pubmed/33767198 http://dx.doi.org/10.1038/s41467-021-22174-4 |
Ejemplares similares
-
Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype
por: Burhop, Annina, et al.
Publicado: (2021) -
Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids
por: Liu, Jie, et al.
Publicado: (2021) -
Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products
por: Liu, Jie, et al.
Publicado: (2021) -
Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor
por: Foley, Daniel J., et al.
Publicado: (2020) -
Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone
por: Grigalunas, Michael, et al.
Publicado: (2022)