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A Genetic Risk Score Improves the Prediction of Type 2 Diabetes Mellitus in Mexican Youths but Has Lower Predictive Utility Compared With Non-Genetic Factors

BACKGROUND: Type 2 diabetes (T2D) is a multifactorial disease caused by a complex interplay between environmental risk factors and genetic predisposition. To date, a total of 10 single nucleotide polymorphism (SNPs) have been associated with pediatric-onset T2D in Mexicans, with a small individual e...

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Detalles Bibliográficos
Autores principales: Miranda-Lora, América Liliana, Vilchis-Gil, Jenny, Juárez-Comboni, Daniel B., Cruz, Miguel, Klünder-Klünder, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994893/
https://www.ncbi.nlm.nih.gov/pubmed/33776940
http://dx.doi.org/10.3389/fendo.2021.647864