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A Genetic Risk Score Improves the Prediction of Type 2 Diabetes Mellitus in Mexican Youths but Has Lower Predictive Utility Compared With Non-Genetic Factors
BACKGROUND: Type 2 diabetes (T2D) is a multifactorial disease caused by a complex interplay between environmental risk factors and genetic predisposition. To date, a total of 10 single nucleotide polymorphism (SNPs) have been associated with pediatric-onset T2D in Mexicans, with a small individual e...
Autores principales: | Miranda-Lora, América Liliana, Vilchis-Gil, Jenny, Juárez-Comboni, Daniel B., Cruz, Miguel, Klünder-Klünder, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994893/ https://www.ncbi.nlm.nih.gov/pubmed/33776940 http://dx.doi.org/10.3389/fendo.2021.647864 |
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