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Polo-Like Kinase 4’s Critical Role in Cancer Development and Strategies for Plk4-Targeted Therapy

Polo-like kinases (Plks) are critical regulatory molecules during the cell cycle process. This family has five members: Plk1, 2, 3, 4, and 5. Plk4 has been identified as a master regulator of centriole replication, and its aberrant expression is closely associated with cancer development. In this re...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaoyang, Wei, Cheng, Liang, Hao, Han, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994899/ https://www.ncbi.nlm.nih.gov/pubmed/33777739 http://dx.doi.org/10.3389/fonc.2021.587554

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