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High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?

BACKGROUND: There is an ongoing debate on a potential protective role of habitual physical activity and passive heat therapy on the risk of COVID‐19, a respiratory infectious disease that can manifest as severe pneumonia. To explore these putative roles, we evaluated the independent and joint associ...

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Autores principales: Kunutsor, Setor K., Laukkanen, Jari A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995101/
https://www.ncbi.nlm.nih.gov/pubmed/33426640
http://dx.doi.org/10.1111/eci.13490
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author Kunutsor, Setor K.
Laukkanen, Jari A.
author_facet Kunutsor, Setor K.
Laukkanen, Jari A.
author_sort Kunutsor, Setor K.
collection PubMed
description BACKGROUND: There is an ongoing debate on a potential protective role of habitual physical activity and passive heat therapy on the risk of COVID‐19, a respiratory infectious disease that can manifest as severe pneumonia. To explore these putative roles, we evaluated the independent and joint associations of cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) with pneumonia risk in a prospective cohort study of 2275 men aged 42‐61 years at recruitment. MATERIAL AND METHODS: Objectively measured CRF and self‐reported sauna bathing habits were assessed at baseline. CRF was categorized as low and high (median cut‐offs) and FSB as low and high (defined as ≤1 and 2‐7 sessions/wk, respectively). Multivariable‐adjusted hazard ratios (HRs) with confidence intervals (CIs) were calculated for incident pneumonia. RESULTS: During a median follow‐up of 26.6 years, 529 cases of pneumonia occurred. Comparing high vs low CRF, the multivariable‐adjusted HR (95% CIs) for pneumonia was 0.75 (0.61‐0.91). Comparing high vs low FSB, the corresponding HR was 0.81 (0.68‐0.97). Compared to men with low CRF & low FSB, the multivariable‐adjusted HRs of pneumonia for the following groups: high CRF & low FSB; low CRF & high FSB; and high CRF & high FSB were 0.88 (0.65‐1.20), 0.89 (0.71‐1.13), and 0.62 (0.48‐0.80) respectively. CONCLUSIONS: In a general male Caucasian population, a combination of high fitness levels and frequent sauna baths is associated with a substantially lowered future pneumonia risk compared with each modality alone. The implications of these findings in altering COVID‐19 disease or its severity deserve study.
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spelling pubmed-79951012021-03-26 High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19? Kunutsor, Setor K. Laukkanen, Jari A. Eur J Clin Invest Original Article BACKGROUND: There is an ongoing debate on a potential protective role of habitual physical activity and passive heat therapy on the risk of COVID‐19, a respiratory infectious disease that can manifest as severe pneumonia. To explore these putative roles, we evaluated the independent and joint associations of cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) with pneumonia risk in a prospective cohort study of 2275 men aged 42‐61 years at recruitment. MATERIAL AND METHODS: Objectively measured CRF and self‐reported sauna bathing habits were assessed at baseline. CRF was categorized as low and high (median cut‐offs) and FSB as low and high (defined as ≤1 and 2‐7 sessions/wk, respectively). Multivariable‐adjusted hazard ratios (HRs) with confidence intervals (CIs) were calculated for incident pneumonia. RESULTS: During a median follow‐up of 26.6 years, 529 cases of pneumonia occurred. Comparing high vs low CRF, the multivariable‐adjusted HR (95% CIs) for pneumonia was 0.75 (0.61‐0.91). Comparing high vs low FSB, the corresponding HR was 0.81 (0.68‐0.97). Compared to men with low CRF & low FSB, the multivariable‐adjusted HRs of pneumonia for the following groups: high CRF & low FSB; low CRF & high FSB; and high CRF & high FSB were 0.88 (0.65‐1.20), 0.89 (0.71‐1.13), and 0.62 (0.48‐0.80) respectively. CONCLUSIONS: In a general male Caucasian population, a combination of high fitness levels and frequent sauna baths is associated with a substantially lowered future pneumonia risk compared with each modality alone. The implications of these findings in altering COVID‐19 disease or its severity deserve study. John Wiley and Sons Inc. 2021-01-22 2021-03 /pmc/articles/PMC7995101/ /pubmed/33426640 http://dx.doi.org/10.1111/eci.13490 Text en © 2021 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kunutsor, Setor K.
Laukkanen, Jari A.
High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?
title High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?
title_full High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?
title_fullStr High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?
title_full_unstemmed High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?
title_short High fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: Are there potential implications for COVID‐19?
title_sort high fitness levels, frequent sauna bathing and risk of pneumonia in a cohort study: are there potential implications for covid‐19?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995101/
https://www.ncbi.nlm.nih.gov/pubmed/33426640
http://dx.doi.org/10.1111/eci.13490
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