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Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles

Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nano‐delivery system for therapeutic nucleic acids. The great effort put in the development of ionizable lipids with increased in vivo potency brought LNPs from the laboratory benches to the FDA approval of patisiran in 2018 and t...

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Detalles Bibliográficos
Autores principales:	Schlich, Michele, Palomba, Roberto, Costabile, Gabriella, Mizrahy, Shoshy, Pannuzzo, Martina, Peer, Dan, Decuzzi, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995196/ https://www.ncbi.nlm.nih.gov/pubmed/33786376 http://dx.doi.org/10.1002/btm2.10213

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