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Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures

Widespread growth signatures in COVID‐19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear, and sublinear). Through analytical and numerical analysis, a novel framework is developed that exploits information in these signatu...

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Detalles Bibliográficos
Autores principales: Djordjevic, Magdalena, Djordjevic, Marko, Ilic, Bojana, Stojku, Stefan, Salom, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995214/
https://www.ncbi.nlm.nih.gov/pubmed/33786198
http://dx.doi.org/10.1002/gch2.202000101
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author Djordjevic, Magdalena
Djordjevic, Marko
Ilic, Bojana
Stojku, Stefan
Salom, Igor
author_facet Djordjevic, Magdalena
Djordjevic, Marko
Ilic, Bojana
Stojku, Stefan
Salom, Igor
author_sort Djordjevic, Magdalena
collection PubMed
description Widespread growth signatures in COVID‐19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear, and sublinear). Through analytical and numerical analysis, a novel framework is developed that exploits information in these signatures. An approach well known to physics is applied, where one looks for common dynamical features, independently from differences in other factors. These features and associated scaling laws are used as a powerful tool to pinpoint regions where analytical derivations are effective, get an insight into qualitative changes of the disease progression, and infer the key infection parameters. The developed framework for joint analytical and numerical analysis of empirically observed COVID‐19 growth patterns can lead to a fundamental understanding of infection progression under strong control measures, applicable to outbursts of both COVID‐19 and other infectious diseases.
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spelling pubmed-79952142021-03-26 Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures Djordjevic, Magdalena Djordjevic, Marko Ilic, Bojana Stojku, Stefan Salom, Igor Glob Chall Communications Widespread growth signatures in COVID‐19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear, and sublinear). Through analytical and numerical analysis, a novel framework is developed that exploits information in these signatures. An approach well known to physics is applied, where one looks for common dynamical features, independently from differences in other factors. These features and associated scaling laws are used as a powerful tool to pinpoint regions where analytical derivations are effective, get an insight into qualitative changes of the disease progression, and infer the key infection parameters. The developed framework for joint analytical and numerical analysis of empirically observed COVID‐19 growth patterns can lead to a fundamental understanding of infection progression under strong control measures, applicable to outbursts of both COVID‐19 and other infectious diseases. John Wiley and Sons Inc. 2021-03-01 /pmc/articles/PMC7995214/ /pubmed/33786198 http://dx.doi.org/10.1002/gch2.202000101 Text en © 2021 The Authors. Global Challenges published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Djordjevic, Magdalena
Djordjevic, Marko
Ilic, Bojana
Stojku, Stefan
Salom, Igor
Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
title Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
title_full Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
title_fullStr Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
title_full_unstemmed Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
title_short Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
title_sort understanding infection progression under strong control measures through universal covid‐19 growth signatures
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995214/
https://www.ncbi.nlm.nih.gov/pubmed/33786198
http://dx.doi.org/10.1002/gch2.202000101
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