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Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures
Widespread growth signatures in COVID‐19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear, and sublinear). Through analytical and numerical analysis, a novel framework is developed that exploits information in these signatu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995214/ https://www.ncbi.nlm.nih.gov/pubmed/33786198 http://dx.doi.org/10.1002/gch2.202000101 |
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author | Djordjevic, Magdalena Djordjevic, Marko Ilic, Bojana Stojku, Stefan Salom, Igor |
author_facet | Djordjevic, Magdalena Djordjevic, Marko Ilic, Bojana Stojku, Stefan Salom, Igor |
author_sort | Djordjevic, Magdalena |
collection | PubMed |
description | Widespread growth signatures in COVID‐19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear, and sublinear). Through analytical and numerical analysis, a novel framework is developed that exploits information in these signatures. An approach well known to physics is applied, where one looks for common dynamical features, independently from differences in other factors. These features and associated scaling laws are used as a powerful tool to pinpoint regions where analytical derivations are effective, get an insight into qualitative changes of the disease progression, and infer the key infection parameters. The developed framework for joint analytical and numerical analysis of empirically observed COVID‐19 growth patterns can lead to a fundamental understanding of infection progression under strong control measures, applicable to outbursts of both COVID‐19 and other infectious diseases. |
format | Online Article Text |
id | pubmed-7995214 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79952142021-03-26 Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures Djordjevic, Magdalena Djordjevic, Marko Ilic, Bojana Stojku, Stefan Salom, Igor Glob Chall Communications Widespread growth signatures in COVID‐19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear, and sublinear). Through analytical and numerical analysis, a novel framework is developed that exploits information in these signatures. An approach well known to physics is applied, where one looks for common dynamical features, independently from differences in other factors. These features and associated scaling laws are used as a powerful tool to pinpoint regions where analytical derivations are effective, get an insight into qualitative changes of the disease progression, and infer the key infection parameters. The developed framework for joint analytical and numerical analysis of empirically observed COVID‐19 growth patterns can lead to a fundamental understanding of infection progression under strong control measures, applicable to outbursts of both COVID‐19 and other infectious diseases. John Wiley and Sons Inc. 2021-03-01 /pmc/articles/PMC7995214/ /pubmed/33786198 http://dx.doi.org/10.1002/gch2.202000101 Text en © 2021 The Authors. Global Challenges published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Communications Djordjevic, Magdalena Djordjevic, Marko Ilic, Bojana Stojku, Stefan Salom, Igor Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures |
title | Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures |
title_full | Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures |
title_fullStr | Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures |
title_full_unstemmed | Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures |
title_short | Understanding Infection Progression under Strong Control Measures through Universal COVID‐19 Growth Signatures |
title_sort | understanding infection progression under strong control measures through universal covid‐19 growth signatures |
topic | Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995214/ https://www.ncbi.nlm.nih.gov/pubmed/33786198 http://dx.doi.org/10.1002/gch2.202000101 |
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