Two distinct conformers of PrP(D) type 1 of sporadic Creutzfeldt–Jakob disease with codon 129VV genotype faithfully propagate in vivo

Current classifications of sporadic Creutzfeldt–Jakob disease (sCJD) identify five subtypes associated with different disease phenotypes. Most of these histopathological phenotypes (histotypes) co-distribute with distinct pairings of methionine (M)/valine (V) genotypes at codon 129 of the prion prot...

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Detalles Bibliográficos
Autores principales: Cali, Ignazio, Espinosa, Juan Carlos, Nemani, Satish K., Marin-Moreno, Alba, Camacho, Manuel V., Aslam, Rabail, Kitamoto, Tetsuyuki, Appleby, Brian S., Torres, Juan Maria, Gambetti, Pierluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995586/
https://www.ncbi.nlm.nih.gov/pubmed/33766126
http://dx.doi.org/10.1186/s40478-021-01132-7

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