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OncoGEMINI: software for investigating tumor variants from multiple biopsies with integrated cancer annotations
BACKGROUND: DNA sequencing has unveiled extensive tumor heterogeneity in several different cancer types, with many exhibiting diverse subclonal populations. Identifying and tracing mutations throughout the expansion and progression of a tumor represents a significant challenge. Furthermore, prioriti...
Autores principales: | Nicholas, Thomas J., Cormier, Michael J., Huang, Xiaomeng, Qiao, Yi, Marth, Gabor T., Quinlan, Aaron R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995589/ https://www.ncbi.nlm.nih.gov/pubmed/33771218 http://dx.doi.org/10.1186/s13073-021-00854-6 |
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