Cargando…

DGCR8-dependent efficient pri-miRNA processing of human pri-miR-9-2

Microprocessor complex, including DiGeorge syndrome critical region gene 8 (DGCR8) and DROSHA, recognizes and cleaves primary transcripts of microRNAs (pri-miRNAs) in the maturation of canonical miRNAs. The study of DGCR8 haploinsufficiency reveals that the efficiency of this activity varies for dif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nogami, Masahiro, Miyamoto, Kazumasa, Hayakawa-Yano, Yoshika, Nakanishi, Atsushi, Yano, Masato, Okano, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995608/ https://www.ncbi.nlm.nih.gov/pubmed/33581109 http://dx.doi.org/10.1016/j.jbc.2021.100409

Ejemplares similares

Select amino acids in DGCR8 are essential for the UGU-pri-miRNA interaction and processing
por: Dang, Thi Lieu, et al.
Publicado: (2020)

Functional Dissection of pri-miR-290~295 in Dgcr8 Knockout Mouse Embryonic Stem Cells
por: Shi, Ming, et al.
Publicado: (2019)

Pri-miR526b and Pri-miR655 Are Potential Blood Biomarkers for Breast Cancer
por: Majumder, Mousumi, et al.
Publicado: (2021)

Introns of plant pri-miRNAs enhance miRNA biogenesis
por: Bielewicz, Dawid, et al.
Publicado: (2013)

Small ORFs as New Regulators of Pri-miRNAs and miRNAs Expression in Human and Drosophila
por: Dozier, Christine, et al.
Publicado: (2022)

mirEX: a platform for comparative exploration of plant pri-miRNA expression data
por: Bielewicz, Dawid, et al.
Publicado: (2012)

Microprocessor dynamics shows co- and post-transcriptional processing of pri-miRNAs
por: Louloupi, Annita, et al.
Publicado: (2017)

NF90 modulates processing of a subset of human pri-miRNAs
por: Grasso, Giuseppa, et al.
Publicado: (2020)

Fluorescence in situ Localization of Pri-miRNAs in Isolated Arabidopsis thaliana Nuclei
por: Gulanicz, Tomasz, et al.
Publicado: (2023)

Evidence That Regulation of Pri-miRNA/miRNA Expression Is Not a General Rule of miPEPs Function in Humans
por: Prel, Anne, et al.
Publicado: (2021)

Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs
por: Nepal, Chirag, et al.
Publicado: (2016)

Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA
por: Kang, Min, et al.
Publicado: (2020)

Gene structures and processing of Arabidopsis thaliana HYL1-dependent pri-miRNAs
por: Szarzynska, Bogna, et al.
Publicado: (2009)

Role of PRY-1/Axin in heterochronic miRNA-mediated seam cell development
por: Mallick, Avijit, et al.
Publicado: (2019)

Bulges control pri-miRNA processing in a position and strand-dependent manner
por: Li, Shaohua, et al.
Publicado: (2020)

Flexible pri-miRNA structures enable tunable production of 5’ isomiRs
por: Bofill-De Ros, Xavier, et al.
Publicado: (2022)

Pri-miR-124 rs531564 polymorphism and colorectal cancer risk
por: Gao, Xue-ren, et al.
Publicado: (2015)

Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 Polymorphisms Are Associated with Decreased Risk of Esophageal Squamous Cell Carcinoma in Chinese Populations
por: Zhang, Junjie, et al.
Publicado: (2014)

The Promoter of the pri-miR-375 Gene Directs Expression Selectively to the Endocrine Pancreas
por: Avnit-Sagi, Tali, et al.
Publicado: (2009)

A pri-miR-218 variant and risk of cervical carcinoma in Chinese women
por: Shi, Ting-Yan, et al.
Publicado: (2013)

Adiós al PRI /
por: Zaid, Gabriel
Publicado: (1995)

Oleic Acid Induces MiR-7 Processing through Remodeling of Pri-MiR-7/Protein Complex
por: Kumar, Santosh, et al.
Publicado: (2017)

Bi-directional processing of pri-miRNAs with branched terminal loops by Arabidopsis Dicer-like1
por: Zhu, Hongliang, et al.
Publicado: (2013)

Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis
por: Köster, Tino, et al.
Publicado: (2014)

A competitive regulatory mechanism discriminates between juxtaposed splice sites and pri-miRNA structures
por: Mattioli, Chiara, et al.
Publicado: (2013)

Association of Polymorphisms in three pri-miRNAs that Target Pepsinogen C with the Risk and Prognosis of Gastric Cancer
por: Wu, Ye-feng, et al.
Publicado: (2017)

The RNA binding protein EWS is broadly involved in the regulation of pri-miRNA processing in mammalian cells
por: Ouyang, Huiwu, et al.
Publicado: (2017)

NEAT1 Scaffolds RNA Binding Proteins and the Microprocessor to Globally Enhance Pri-miRNA Processing
por: Jiang, Li, et al.
Publicado: (2017)

Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing
por: Conrad, Thomas, et al.
Publicado: (2020)

mRNA adenosine methylase (MTA) deposits m(6)A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana
por: Bhat, Susheel Sagar, et al.
Publicado: (2020)

What "Panel-Prying" Really Is
Publicado: (1921)

Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires
por: Bofill-De Ros, Xavier, et al.
Publicado: (2019)

Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format
por: Brachtlova, Tereza, et al.
Publicado: (2020)

R-loops at microRNA encoding loci promote co-transcriptional processing of pri-miRNAs in plants
por: Gonzalo, Lucia, et al.
Publicado: (2022)

Structural Insight into the DNA-Binding Mode of the Primosomal Proteins PriA, PriB, and DnaT
por: Huang, Yen-Hua, et al.
Publicado: (2014)

Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha
por: Diaz, Jason P., et al.
Publicado: (2014)

Association Between Genetic Variant in the Promoter of Pri-miR-34b/c and Risk of Glioma
por: Li, Jinghui, et al.
Publicado: (2018)

Hydrogen Sulfide Improves Angiogenesis by Regulating the Transcription of pri-miR-126 in Diabetic Endothelial Cells
por: Xue, Wenlong, et al.
Publicado: (2022)

FTO-mediated m6A demethylation of pri-miR-3591 alleviates osteoarthritis progression
por: Liu, Wengang, et al.
Publicado: (2023)

Identification of genetic interactions with priB links the PriA/PriB DNA replication restart pathway to double-strand DNA break repair in Escherichia coli
por: McKenzie, Aidan M, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3ovhq82urej6nuaattnoubsn66