Exploring the landscape of ectodomain shedding by quantitative protein terminomics

Ectodomain shedding is a proteolytic process that regulates the levels and functions of membrane proteins. Dysregulated shedding is linked to severe diseases, including cancer and Alzheimer's disease. However, the exact cleavage sites of shedding substrates remain largely unknown. Here, we expl...

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Detalles Bibliográficos
Autores principales: Tsumagari, Kazuya, Chang, Chih-Hsiang, Ishihama, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995609/
https://www.ncbi.nlm.nih.gov/pubmed/33796845
http://dx.doi.org/10.1016/j.isci.2021.102259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995609/
https://www.ncbi.nlm.nih.gov/pubmed/33796845
http://dx.doi.org/10.1016/j.isci.2021.102259

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