Cargando…
Exploring the landscape of ectodomain shedding by quantitative protein terminomics
Ectodomain shedding is a proteolytic process that regulates the levels and functions of membrane proteins. Dysregulated shedding is linked to severe diseases, including cancer and Alzheimer's disease. However, the exact cleavage sites of shedding substrates remain largely unknown. Here, we expl...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995609/ https://www.ncbi.nlm.nih.gov/pubmed/33796845 http://dx.doi.org/10.1016/j.isci.2021.102259 |