Dihydroxyacetone phosphate signals glucose availability to mTORC1

The mTOR complex 1 (mTORC1) kinase regulates cell growth by setting the balance between anabolic and catabolic processes. To be active, mTORC1 requires the environmental presence of amino acids and glucose. While a mechanistic understanding of amino acid sensing by mTORC1 is emerging, how glucose ac...

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Detalles Bibliográficos
Autores principales: Orozco, Jose M., Krawczyk, Patrycja A., Scaria, Sonia M., Cangelosi, Andrew L., Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A., Sabatini, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995735/
https://www.ncbi.nlm.nih.gov/pubmed/32719541
http://dx.doi.org/10.1038/s42255-020-0250-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995735/
https://www.ncbi.nlm.nih.gov/pubmed/32719541
http://dx.doi.org/10.1038/s42255-020-0250-5

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