Human AZFb deletions cause distinct testicular pathologies depending on their extensions in Yq11 and the Y haplogroup: new cases and review of literature

Genomic AZFb deletions in Yq11 coined “classical” (i.e. length of Y DNA deletion: 6.23 Mb) are associated with meiotic arrest (MA) of patient spermatogenesis, i.e., absence of any postmeiotic germ cells. These AZFb deletions are caused by non-allelic homologous recombination (NAHR) events between id...

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Detalles Bibliográficos
Autores principales: Vogt, P. H., Bender, U., Deibel, B., Kiesewetter, F., Zimmer, J., Strowitzki, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995748/
https://www.ncbi.nlm.nih.gov/pubmed/33766143
http://dx.doi.org/10.1186/s13578-021-00551-2

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