The Nucleocapsid Protein of Severe Acute Respiratory Syndrome-Coronavirus Inhibits the Activity of Cyclin-Cyclin-dependent Kinase Complex and Blocks S Phase Progression in Mammalian Cells

Deregulation of the cell cycle is a common strategy employed by many DNA and RNA viruses to trap and exploit the host cell machinery toward their own benefit. In many coronaviruses, the nucleocapsid protein (N protein) has been shown to inhibit cell cycle progression although the mechanism behind th...

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Detalles Bibliográficos
Autores principales: Surjit, Milan, Liu, Boping, Chow, Vincent T.K., Lal, Sunil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2006
Materias:
Enzyme Catalysis and Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995956/
https://www.ncbi.nlm.nih.gov/pubmed/16431923
http://dx.doi.org/10.1074/jbc.M509233200

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