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Guanosine-5′-triphosphate cyclohydrolase 1 regulated long noncoding RNAs are potential targets for microglial activation in neuropathic pain

Several studies have confirmed that microglia are involved in neuropathic pain. Inhibition of guanosine-5′-triphosphate cyclohydrolase 1 (GTPCH1) can reduce the inflammation of microglia. However, the precise mechanism by which GTPCH1 regulates neuropathic pain remains unclear. In this study, BV2 mi...

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Detalles Bibliográficos
Autores principales: Liang, Yan-Hu, Chen, Guo-Wu, Li, Xue-Song, Jia, Shu, Meng, Chun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996028/
https://www.ncbi.nlm.nih.gov/pubmed/32985494
http://dx.doi.org/10.4103/1673-5374.290914