Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation

Endothelial barrier disruption and vascular leak importantly contribute to organ dysfunction and mortality during inflammatory conditions like sepsis and acute respiratory distress syndrome. We identified the kinase Arg/Abl2 as a mediator of endothelial barrier disruption, but the role of Arg in end...

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Detalles Bibliográficos
Autores principales: Amado-Azevedo, Joana, van Stalborch, Anne-Marieke D., Valent, Erik T., Nawaz, Kalim, van Bezu, Jan, Eringa, Etto C., Hoevenaars, Femke P. M., De Cuyper, Iris M., Hordijk, Peter L., van Hinsbergh, Victor W. M., van Nieuw Amerongen, Geerten P., Aman, Jurjan, Margadant, Coert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996118/
https://www.ncbi.nlm.nih.gov/pubmed/33770321
http://dx.doi.org/10.1007/s10456-021-09781-x

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