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Ibrexafungerp: A First-in-Class Oral Triterpenoid Glucan Synthase Inhibitor
Ibrexafungerp (formerly SCY-078 or MK-3118) is a first-in-class triterpenoid antifungal or “fungerp” that inhibits biosynthesis of β-(1,3)-D-glucan in the fungal cell wall, a mechanism of action similar to that of echinocandins. Distinguishing characteristics of ibrexafungerp include oral bioavailab...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996284/ https://www.ncbi.nlm.nih.gov/pubmed/33668824 http://dx.doi.org/10.3390/jof7030163 |