Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains

Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to...

Descripción completa

Detalles Bibliográficos
Autores principales: Renner, Daniel W., Parsons, Lance, Shreve, Jacob T., Engel, Esteban A., Kuny, Chad V., Enquist, Lynn, Neumann, Donna, Mangold, Colleen, Szpara, Moriah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996463/
https://www.ncbi.nlm.nih.gov/pubmed/33766904
http://dx.doi.org/10.1128/MRA.01146-19
Descripción
Sumario:Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.

Ejemplares similares