Cargando…

Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine

The mRNA-1273 vaccine, popularly called the "Moderna vaccine" is being widely administered in the United States for the prevention of COVID-19 infection since December 2020. Mild to moderate intensity side effects like low-grade fever, myalgia, chills and malaise were reported in the trial...

Descripción completa

Detalles Bibliográficos
Autores principales: Malayala, Srikrishna V, Mohan, Gisha, Vasireddy, Deepa, Atluri, Paavani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996471/
https://www.ncbi.nlm.nih.gov/pubmed/33786251
http://dx.doi.org/10.7759/cureus.14099
_version_ 1783670110394777600
author Malayala, Srikrishna V
Mohan, Gisha
Vasireddy, Deepa
Atluri, Paavani
author_facet Malayala, Srikrishna V
Mohan, Gisha
Vasireddy, Deepa
Atluri, Paavani
author_sort Malayala, Srikrishna V
collection PubMed
description The mRNA-1273 vaccine, popularly called the "Moderna vaccine" is being widely administered in the United States for the prevention of COVID-19 infection since December 2020. Mild to moderate intensity side effects like low-grade fever, myalgia, chills and malaise were reported in the trials related to the vaccine. With this case report, we report a case of purpuric rash and thrombocytopenia after receiving the first dose of the m-RNA-1273 vaccine. The patient, in this case, is a 60-year-old male patient who received the first vaccine dose and within two days, he developed diffuse papular rash associated with some thrombocytopenia. He had a history of tobacco use, Hepatitis C liver cirrhosis, chronic kidney disease stage 4, untreated hypertension and systolic congestive heart failure at the baseline. With review of the limited literature related to the vaccine and its side effect profile and with no other etiology explaining the sudden onset of rash, we attribute this thrombocytopenia and purpuric rash as the side effects of the mRNA-1273 vaccine.
format Online
Article
Text
id pubmed-7996471
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-79964712021-03-29 Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine Malayala, Srikrishna V Mohan, Gisha Vasireddy, Deepa Atluri, Paavani Cureus Dermatology The mRNA-1273 vaccine, popularly called the "Moderna vaccine" is being widely administered in the United States for the prevention of COVID-19 infection since December 2020. Mild to moderate intensity side effects like low-grade fever, myalgia, chills and malaise were reported in the trials related to the vaccine. With this case report, we report a case of purpuric rash and thrombocytopenia after receiving the first dose of the m-RNA-1273 vaccine. The patient, in this case, is a 60-year-old male patient who received the first vaccine dose and within two days, he developed diffuse papular rash associated with some thrombocytopenia. He had a history of tobacco use, Hepatitis C liver cirrhosis, chronic kidney disease stage 4, untreated hypertension and systolic congestive heart failure at the baseline. With review of the limited literature related to the vaccine and its side effect profile and with no other etiology explaining the sudden onset of rash, we attribute this thrombocytopenia and purpuric rash as the side effects of the mRNA-1273 vaccine. Cureus 2021-03-25 /pmc/articles/PMC7996471/ /pubmed/33786251 http://dx.doi.org/10.7759/cureus.14099 Text en Copyright © 2021, Malayala et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Malayala, Srikrishna V
Mohan, Gisha
Vasireddy, Deepa
Atluri, Paavani
Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine
title Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine
title_full Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine
title_fullStr Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine
title_full_unstemmed Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine
title_short Purpuric Rash and Thrombocytopenia After the mRNA-1273 (Moderna) COVID-19 Vaccine
title_sort purpuric rash and thrombocytopenia after the mrna-1273 (moderna) covid-19 vaccine
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996471/
https://www.ncbi.nlm.nih.gov/pubmed/33786251
http://dx.doi.org/10.7759/cureus.14099
work_keys_str_mv AT malayalasrikrishnav purpuricrashandthrombocytopeniaafterthemrna1273modernacovid19vaccine
AT mohangisha purpuricrashandthrombocytopeniaafterthemrna1273modernacovid19vaccine
AT vasireddydeepa purpuricrashandthrombocytopeniaafterthemrna1273modernacovid19vaccine
AT atluripaavani purpuricrashandthrombocytopeniaafterthemrna1273modernacovid19vaccine