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RNA Helicase A Regulates the Replication of RNA Viruses
The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus rep...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996507/ https://www.ncbi.nlm.nih.gov/pubmed/33668948 http://dx.doi.org/10.3390/v13030361 |
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author | Shi, Rui-Zhu Pan, Yuan-Qing Xing, Li |
author_facet | Shi, Rui-Zhu Pan, Yuan-Qing Xing, Li |
author_sort | Shi, Rui-Zhu |
collection | PubMed |
description | The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview of the role of RHA in the replication of RNA viruses. |
format | Online Article Text |
id | pubmed-7996507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79965072021-03-27 RNA Helicase A Regulates the Replication of RNA Viruses Shi, Rui-Zhu Pan, Yuan-Qing Xing, Li Viruses Review The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview of the role of RHA in the replication of RNA viruses. MDPI 2021-02-25 /pmc/articles/PMC7996507/ /pubmed/33668948 http://dx.doi.org/10.3390/v13030361 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Review Shi, Rui-Zhu Pan, Yuan-Qing Xing, Li RNA Helicase A Regulates the Replication of RNA Viruses |
title | RNA Helicase A Regulates the Replication of RNA Viruses |
title_full | RNA Helicase A Regulates the Replication of RNA Viruses |
title_fullStr | RNA Helicase A Regulates the Replication of RNA Viruses |
title_full_unstemmed | RNA Helicase A Regulates the Replication of RNA Viruses |
title_short | RNA Helicase A Regulates the Replication of RNA Viruses |
title_sort | rna helicase a regulates the replication of rna viruses |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996507/ https://www.ncbi.nlm.nih.gov/pubmed/33668948 http://dx.doi.org/10.3390/v13030361 |
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