Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy

BACKGROUND: The cancer-testis antigen MAGE-A4 is an attractive target for T-cell-based immunotherapy, especially for indications with unmet clinical need like non-small cell lung or triple-negative breast cancer. METHODS: An unbiased CD137-based sorting approach was first used to identify an immunog...

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Detalles Bibliográficos
Autores principales: Davari, Kathrin, Holland, Tristan, Prassmayer, Laura, Longinotti, Giulia, Ganley, Kenneth P, Pechilis, Lisa J, Diaconu, Iulia, Nambiar, Prashant R, Magee, Michael S, Schendel, Dolores J, Sommermeyer, Daniel, Ellinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996660/
https://www.ncbi.nlm.nih.gov/pubmed/33771892
http://dx.doi.org/10.1136/jitc-2020-002035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996660/
https://www.ncbi.nlm.nih.gov/pubmed/33771892
http://dx.doi.org/10.1136/jitc-2020-002035

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