Cargando…

Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis

Hypopharyngeal squamous cell carcinoma (HSCC) is usually diagnosed at an advanced stage, leading to a poor prognosis. Even after improvement of surgical techniques, chemotherapy, and radiation technology, the survival rate of HSCC remains poor. Metformin, which is commonly used for type 2 diabetes m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsou, Yung-An, Chang, Wei-Chao, Lin, Chia-Der, Chang, Ro-Lin, Tsai, Ming-Hsui, Shih, Liang-Chun, Staniczek, Theresa, Wu, Tsu-Fang, Hsu, Hui-Ying, Chang, Wen-Dien, Lai, Chih-Ho, Chen, Chuan-Mu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996771/ https://www.ncbi.nlm.nih.gov/pubmed/33652909 http://dx.doi.org/10.3390/ph14030191

Ejemplares similares

The effect of metformin use on hypopharyngeal squamous cell carcinoma in diabetes mellitus patients
por: Tsou, Yung-An, et al.
Publicado: (2019)

Additive Antiproliferative and Antiangiogenic Effects of Metformin and Pemetrexed in a Non-Small-Cell Lung Cancer Xenograft Model
por: Wang, Jiun-Long, et al.
Publicado: (2021)

Trans-oral robotic surgery versus coblation tongue base reduction for obstructive sleep apnea syndrome
por: Lan, Wei-Che, et al.
Publicado: (2019)

Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis
por: Chang, Wen-Dien, et al.
Publicado: (2021)

Benefits of Metformin Combined with Pemetrexed-Based Platinum Doublets as a First-Line Therapy for Advanced Lung Adenocarcinoma Patients with Diabetes
por: Wang, Jiun-Long, et al.
Publicado: (2021)

The Role of BPIFA1 in Upper Airway Microbial Infections and Correlated Diseases
por: Tsou, Yung-An, et al.
Publicado: (2018)

Treatment patterns and survival outcomes of advanced hypopharyngeal squamous cell carcinoma
por: Tsai, Yao-Te, et al.
Publicado: (2020)

Combined Transoral Robotic Tongue Base Surgery and Palate Surgery in Obstructive Sleep Apnea Syndrome: Modified Uvulopalatopharyngoplasty versus Barbed Reposition Pharyngoplasty
por: Tsou, Yung-An, et al.
Publicado: (2021)

Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
por: Tsou, Yung-An, et al.
Publicado: (2021)

Small B cell lymphocytic lymphoma presenting as obstructive sleep apnea
por: Tsou, Yung-An, et al.
Publicado: (2004)

Interleukin-13 Inhibits Lipopolysaccharide-Induced BPIFA1 Expression in Nasal Epithelial Cells
por: Tsou, Yung-An, et al.
Publicado: (2015)

Comparison of Findings between Clinical Examinations and Drug-Induced Sleep Endoscopy in Patients with Obstructive Sleep Apnea Syndrome
por: Lin, Huan-Yu, et al.
Publicado: (2020)

Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency
por: Chang, Ming-Yang, et al.
Publicado: (2017)

Methylation-Associated Gene Silencing of RARB in Areca Carcinogens Induced Mouse Oral Squamous Cell Carcinoma
por: Lai, Zi-Lun, et al.
Publicado: (2014)

Hypothyroidism and related comorbidities on the risks of developing tinnitus
por: Hsu, Alan, et al.
Publicado: (2022)

Mean platelet volume levels in children with sleep-disordered breathing: a meta-analysis
por: Chang, Wen-Dien, et al.
Publicado: (2020)

Validation of Pharyngeal Acid Reflux Episodes Using Hypopharyngeal Multichannel Intraluminal Impedance-pH
por: Chen, Yen-Yang, et al.
Publicado: (2023)

Using Innovative Acoustic Analysis to Predict the Postoperative Outcomes of Unilateral Vocal Fold Paralysis
por: Tsou, Yung-An, et al.
Publicado: (2016)

Comparison of transoral robotic surgery with other surgeries for obstructive sleep apnea
por: Tsou, Yung-An, et al.
Publicado: (2020)

The effect of tongue base suspension with uvulopalato-pharyngoplasty on sleep quality in obstructive sleep apnea
por: Tsou, Yung-An, et al.
Publicado: (2018)

Absorbable and nonabsorbable packing after functional endoscopic sinus surgery: systematic review and meta-analysis of outcomes
por: Wang, Tang-Chuan, et al.
Publicado: (2014)

Distinct Failure Patterns in Hypopharyngeal Cancer Patients Receiving Surgery-Based Versus Radiation-Based Treatment
por: Lin, Yu-Hsuan, et al.
Publicado: (2022)

Increased risk of Eustachian tube disorders in patients with sleep-disordered breathing
por: Chou, Meng-Shih, et al.
Publicado: (2017)

Effects of Whole-Body Vibration and Balance Training on Female Athletes with Chronic Ankle Instability
por: Chang, Wen-Dien, et al.
Publicado: (2021)

The Changes in the Severity of Deep Neck Infection Post-UPPP and Tonsillectomy in Patients with OSAS
por: Hu, Pin-Ching, et al.
Publicado: (2022)

Carotid arterial blowout after organ preserving chemoradiation therapy in hypopharyngeal cancer
por: Padua, Paula Francezca, et al.
Publicado: (2022)

Prospective Investigation of (18)FDG-PET/MRI with Intravoxel Incoherent Motion Diffusion-Weighted Imaging to Assess Survival in Patients with Oropharyngeal or Hypopharyngeal Carcinoma
por: Chan, Sheng-Chieh, et al.
Publicado: (2022)

Chronic rhinosinusitis and premorbid autoimmune diseases: a population-based case–control study
por: Shih, Liang-Chun, et al.
Publicado: (2020)

Routine Endoscopy for Esophageal Cancer Is Suggestive for Patients with Oral, Oropharyngeal and Hypopharyngeal Cancer
por: Hung, Shih-Han, et al.
Publicado: (2013)

Impact of patient-related factors on successful autologous fat injection laryngoplasty in thyroid surgical treated related unilateral vocal fold paralysis- observational study
por: Lin, Wen-Yang, et al.
Publicado: (2020)

Oxidative Stress Biomarkers and Mitochondrial DNA Copy Number Associated with APOE4 Allele and Cholinesterase Inhibitor Therapy in Patients with Alzheimer’s Disease
por: Liou, Chia-Wei, et al.
Publicado: (2021)

Correction: Routine Endoscopy for Esophageal Cancer Is Suggestive for Patients with Oral, Oropharyngeal and Hypopharyngeal Cancer
por: Hung, Shih-Han, et al.
Publicado: (2017)

Protective effect of metformin against retinal vein occlusions in diabetes mellitus – A nationwide population-based study
por: Lin, Tai-Chi, et al.
Publicado: (2017)

Intensity modulated radiotherapy with concurrent chemotherapy for larynx preservation of advanced resectable hypopharyngeal cancer
por: Huang, Wen-Yen, et al.
Publicado: (2010)

Cranial Electrotherapy Stimulation to Improve the Physiology and Psychology Response, Response-Ability, and Sleep Efficiency in Athletes with Poor Sleep Quality
por: Chang, Wen-Dien, et al.
Publicado: (2022)

Metformin and the Incidence of Cancer in Patients With Diabetes: A Nested Case-Control Study
por: Wang, Shu-Yi, et al.
Publicado: (2013)

Survival analyses of different treatment modalities and clinical stage for hypopharyngeal carcinoma
por: Lin, Tian-Yun, et al.
Publicado: (2023)

A Meta-analysis of Clinical Effects of Low-level Laser Therapy on Temporomandibular Joint Pain
por: Chang, Wen-Dien, et al.
Publicado: (2014)

Autologous Fat Plus Platelet-Rich Plasma versus Autologous Fat Alone on Sulcus Vocalis
por: Tsou, Yung-An, et al.
Publicado: (2022)

Impact of Metformin Use on Survival in Patients with Gastric Cancer and Diabetes Mellitus Following Gastrectomy
por: Chung, Wai-Shan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dvkvguhf97a0k8cln2i6ntbo6g