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Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin

Lutein is a challenging compound to incorporate into food, as it is poorly soluble and unstable in aqueous solutions. In this study, the aim was to prepare stable encapsulates of lutein and lutein esters using feasible and straightforward techniques. Fine suspensions based on polyoxyethylene sorbita...

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Autores principales: Gombač, Zala, Osojnik Črnivec, Ilja Gasan, Skrt, Mihaela, Istenič, Katja, Knez Knafelj, Andreja, Pravst, Igor, Poklar Ulrih, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996776/
https://www.ncbi.nlm.nih.gov/pubmed/33652594
http://dx.doi.org/10.3390/foods10030500
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author Gombač, Zala
Osojnik Črnivec, Ilja Gasan
Skrt, Mihaela
Istenič, Katja
Knez Knafelj, Andreja
Pravst, Igor
Poklar Ulrih, Nataša
author_facet Gombač, Zala
Osojnik Črnivec, Ilja Gasan
Skrt, Mihaela
Istenič, Katja
Knez Knafelj, Andreja
Pravst, Igor
Poklar Ulrih, Nataša
author_sort Gombač, Zala
collection PubMed
description Lutein is a challenging compound to incorporate into food, as it is poorly soluble and unstable in aqueous solutions. In this study, the aim was to prepare stable encapsulates of lutein and lutein esters using feasible and straightforward techniques. Fine suspensions based on polyoxyethylene sorbitan monooleate and medium-chain triglyceride oil micelle-like units with 3.45% lutein esters or 1.9% lutein equivalents provided high encapsulation efficiencies of 79% and 83%, respectively. Lutein encapsulated in fine suspensions showed superior stability, as 86% was retained within the formulation over 250 days at 25 °C in the dark. Under the same storage conditions, only 38% of lutein remained in corresponding formulations. Higher encapsulation efficiencies were achieved with lecithin emulsions, at up to 99.3% for formulations with lutein, and up to 91.4% with lutein esters. In lecithin emulsions that were stored for 250 days, 17% and 80% of lutein and lutein esters, respectively, were retained within the formulations.
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spelling pubmed-79967762021-03-27 Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin Gombač, Zala Osojnik Črnivec, Ilja Gasan Skrt, Mihaela Istenič, Katja Knez Knafelj, Andreja Pravst, Igor Poklar Ulrih, Nataša Foods Article Lutein is a challenging compound to incorporate into food, as it is poorly soluble and unstable in aqueous solutions. In this study, the aim was to prepare stable encapsulates of lutein and lutein esters using feasible and straightforward techniques. Fine suspensions based on polyoxyethylene sorbitan monooleate and medium-chain triglyceride oil micelle-like units with 3.45% lutein esters or 1.9% lutein equivalents provided high encapsulation efficiencies of 79% and 83%, respectively. Lutein encapsulated in fine suspensions showed superior stability, as 86% was retained within the formulation over 250 days at 25 °C in the dark. Under the same storage conditions, only 38% of lutein remained in corresponding formulations. Higher encapsulation efficiencies were achieved with lecithin emulsions, at up to 99.3% for formulations with lutein, and up to 91.4% with lutein esters. In lecithin emulsions that were stored for 250 days, 17% and 80% of lutein and lutein esters, respectively, were retained within the formulations. MDPI 2021-02-26 /pmc/articles/PMC7996776/ /pubmed/33652594 http://dx.doi.org/10.3390/foods10030500 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Gombač, Zala
Osojnik Črnivec, Ilja Gasan
Skrt, Mihaela
Istenič, Katja
Knez Knafelj, Andreja
Pravst, Igor
Poklar Ulrih, Nataša
Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin
title Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin
title_full Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin
title_fullStr Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin
title_full_unstemmed Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin
title_short Stabilisation of Lutein and Lutein Esters with Polyoxyethylene Sorbitan Monooleate, Medium-Chain Triglyceride Oil and Lecithin
title_sort stabilisation of lutein and lutein esters with polyoxyethylene sorbitan monooleate, medium-chain triglyceride oil and lecithin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996776/
https://www.ncbi.nlm.nih.gov/pubmed/33652594
http://dx.doi.org/10.3390/foods10030500
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