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Cholesterol Activates Cyclic AMP Signaling in Metaplastic Acinar Cells

Cholesterol is a non-essential metabolite that exerts both structural and signaling functions. However, cholesterol biosynthesis is elevated, and actively supports, pancreatic carcinogenesis. Our previous work showed that statins block the reprogramming of mutant KRAS-expressing acinar cells, that s...

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Detalles Bibliográficos
Autores principales:	Grisan, Francesca, Spacci, Martina, Paoli, Carlotta, Costamagna, Andrea, Fantuz, Marco, Martini, Miriam, Lefkimmiatis, Konstantinos, Carrer, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996857/ https://www.ncbi.nlm.nih.gov/pubmed/33652890 http://dx.doi.org/10.3390/metabo11030141

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