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Immunity to TBEV Related Flaviviruses with Reduced Pathogenicity Protects Mice from Disease but Not from TBEV Entry into the CNS
Tick-borne encephalitis virus (TBEV) is a leading cause of vector-borne viral encephalitis with expanding endemic regions across Europe. In this study we tested in mice the efficacy of preinfection with a closely related low-virulent flavivirus, Langat virus (LGTV strain TP21), or a naturally avirul...
Autores principales: | Petry, Monique, Palus, Martin, Leitzen, Eva, Mitterreiter, Johanna Gracia, Huang, Bei, Kröger, Andrea, Verjans, Georges M. G. M., Baumgärtner, Wolfgang, Rimmelzwaan, Guus F., Růžek, Daniel, Osterhaus, Albert, Prajeeth, Chittappen Kandiyil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996866/ https://www.ncbi.nlm.nih.gov/pubmed/33652698 http://dx.doi.org/10.3390/vaccines9030196 |
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