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The Controversial Role of Autophagy in Ewing Sarcoma Pathogenesis—Current Treatment Options

Ewing Sarcoma (ES) is a rare, aggressive, and highly metastasizing cancer in children and young adults. Most ES cases carry the fusion of the Ewing Sarcoma Breakpoint Region 1 (EWSR1) and FLI1 (Friend leukemia virus integration site 1) genes, leading to an EWS–FLI1 fused protein, which is associated...

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Detalles Bibliográficos
Autores principales: Koustas, Evangelos, Sarantis, Panagiotis, Karamouzis, Michalis V., Vielh, Philippe, Theocharis, Stamatios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996923/
https://www.ncbi.nlm.nih.gov/pubmed/33652741
http://dx.doi.org/10.3390/biom11030355